SCIENTIFIC PUBLICATIONS
Matheus, A., Samer, G., Lu, W. et al. Machine learning polysomnographically-derived electroencephalography biomarkers predictive of epworth sleepiness scale. Sci Rep 13, 9120 (2023). https://doi.org/10.1038/s41598-023-34716-5
Helen Valsamis, Samah Abdul Baki, Jason Leung, Samer Ghosn, Brittany Lapin, Geetha Chari, Izad-Yar Rasheed, Jaehan Park, Vineet Punia, Dileep Nair, Ann Marie Kaniecki, Muhammad Edhi, Carl Y Saab. SARS-CoV-2 slows brain rhythms with more severe effects in younger Individuals. (2022) Jan 12; https://doi.org/10.21203/rs.3.rs-1197196/v1
Davis, K.D., Aghaeepour, N., Ahn, A.H. et al. Discovery and validation of biomarkers to aid the development of safe and effective pain therapeutics: challenges and opportunities. Nat Rev Neurol 16, 381–400 (2020). https://doi.org/10.1038/s41582-020-0362-2
Levitt J, Edhi MM, Thorpe RV, Leung JW, Michishita M, Koyama S, Yoshikawa S, Scarfo KA, Carayannopoulos AG, Gu W, Srivastava KH, Clark BA, Esteller R, Borton DA, Jones SR, Saab CY. Pain phenotypes classified by machine learning using electroencephalography features. Neuroimage. 2020 Dec;223:117256. doi: 10.1016/j.neuroimage.2020.117256. Epub (2020) Aug 29. PMID: 32871260.
Levitt J, Saab CY. What does a pain 'biomarker' mean and can a machine be taught to measure pain? Neurosci Lett. pii: S0304-3940(18)30824-3 (2018). doi: 10.1016/j.neulet.2018.11.038. [Epub] Review. PMID: 30503919
Koyama S, LeBlanc BW, Smith KA, Roach C, Levitt J, Edhi MM, Michishita M, Komatsu T, Mashita O, Tanikawa A, Yoshikawa S, Saab CY. An Electroencephalography Bioassay for Preclinical Testing of Analgesic Efficacy. Sci Rep. (2018) DOI: 10.1038/s41598-018-34594-2.
Levitt J, Nitenson A, Koyama S, Heijmans L, Curry J, Ross JT, Kamerling S, Saab CY. Automated Detection of Electroencephalography Artifacts in Human, Rodent and Canine Subjects using Machine Learning. Journal of Neuroscience Methods (2018), DOI: 10.1016/j.jneumeth.2018.06.014
Saab CY. Pain-related changes in the brain: diagnostic and therapeutic potentials. Trends in Neuroscience (2012), DOI: 10.1016/j.tins.2012.06.002
Saab C. Visualizing the complex brain dynamics of chronic pain. Journal of Neuroimmune Pharmacology (2013), DOI: 10.1007/s11481-012-9378-8
News and Updates
How An Objective Measure of Pain Could Counter Bias In Medicine
Pain Never Comes in a Pure Form
New Method for Diagnosing Pain Combines EEG and Artificial Intelligence
A New Prognosis for Pain Care
https://www.wsj.com/articles/a-new-prognosis-for-pain-care-11549508700
EEG Test Provides More Effective Way to Measure Pain
https://www.byuradio.org/episode/b36d0128-3422-4c37-8248-a705f0536d82?playhead=4142&autoplay=true
Brown researchers develop new test to objectively measure pain, test medications
https://news.brown.edu/articles/2018/11/pain
